Paullinia Cupana (Guarana)

Paullinia Cupana (Guarana)

Paullinia Cupana (Guarana)

Unveiling the Power of Paullinia Cupana (Guarana)

Recognised for its therapeutic effects and myriad health benefits, Paullinia cupana, commonly known as Guarana, has made a notable mark in the supplement industry. Originating from the Amazon rainforests, this climbing plant boasting small, red fruits has been leveraged in traditional medicine over many centuries. In this article, we delve into what Paullinia cupana is, its benefits, mode of action, recommended dosage, potential side effects, and how it is used.


Deciphering Paullinia cupana (Guarana)

Belonging to the Sapindaceous family, Paullinia cupana, or Guarana, is characterised by its heart-shaped leaves and bright red fruits containing black seeds. These seeds are teeming with dietary and medicinal properties, providing an array of health benefits (1).

Esteemed in indigenous Brazilian cultures, Guarana has found its way into many supplements, remedies, and traditional medicines. Recent studies have highlighted its energising properties and potential health benefits, making Paullinia cupana a critical component of numerous health supplements due to its organic nature and proven positive effects on overall well-being.


The Role of Paullinia cupana

Paullinia cupana stands out as an organic source of several health-promoting ingredients. Its longstanding use in traditional medicine and supplements testifies to its reliability. Regular intake of Paullinia cupana, as recent studies suggest, provides a multitude of benefits:


Energises the Body:

Guarana's claim to fame is primarily due to its energy-boosting capabilities suitable for individuals of all age groups. This attribute is linked to the caffeine found in the black seeds of Guarana, which boasts one of the highest concentrations of caffeine in nature, providing a sustained release of energy-boosting effects (2). 

Notably, Guarana can help combat fatigue, enhance physical endurance, and increase stamina. Unlike synthetic products, the slow release of caffeine from Guarana ensures no rapid spikes or crashes, thus safeguarding mental and physical health.


Enhances Mental Clarity:

Guarana's cognitive-enhancing abilities improve mental alertness, focus, and concentration. The caffeine content stimulates the central nervous system, thereby boosting mental clarity. Guarana also contains compounds like theophylline and theobromine, contributing to overall mental health and cognitive abilities (3).


Aids in Weight Management:

Research indicates that regular use of Guarana can assist in shedding excess weight. Caffeine boosts metabolic processes, which helps utilise the body's existing energy sources. Once the circulating glucose is consumed, the body taps into another energy source - fat. Guarana mobilises fat, utilising it for bodily functions. 


Offers Antioxidative Activity:

Packed with natural antioxidants, Guarana helps neutralise free radicals in the body, which are produced during various chemical reactions. By reducing the load of free radicals and oxidative stress, Guarana effectively prevents undesired inflammatory reactions in the body (4).


Supports Digestive Health:

Another benefit of consuming Paullinia cupana or Guarana is its potential to improve overall digestive health. Caffeine is known to boost the digestive process by speeding up energy utilisation at the cellular level. Improved digestion leads to better absorption of nutrients from food. 

Beyond the benefits mentioned above, Paullinia cupana also positively impacts the cardiovascular and immune systems, liver, and circulation. However, to ensure these benefits, adhering to the labelled dose of the supplement is crucial.


Unravelling the Function of Paullinia cupana

The crucial ingredient in Guarana is caffeine, which serves as an energy source for the body. This well-known stimulant increases metabolism and augments the function of vital organs by acting on the central nervous system. It achieves this by blocking the action of adenosine, a neurotransmitter that promotes relaxation and sleepiness while stimulating the production of mood and alertness-enhancing neurotransmitters like dopamine and noradrenaline (3).

What sets Guarana apart from its peers is its unique composition. The caffeine found in Guarana is bound to tannins, which results in a gradual release of caffeine, providing sustained energy to the body. This contrasts with the sudden energy jolt that synthetic caffeine sources often deliver, which can have detrimental effects on mental health.


Recommended Dosage of Paullinia cupana

The suggested dosage of Guarana depends on several factors such as age, gender, overall health, and individual sensitivity to caffeine. Guarana is available in varying formulations and concentrations; hence, following the manufacturer's guidelines is crucial. Consulting a healthcare provider for personalised advice and dosage is always prudent. 

In general, a dosage of 200 to 400 mg of Guarana is deemed safe for oral consumption in supplement form (5). The overall concentration of caffeine in the supplement should lie between 4 to 6%. For those taking Paullinia cupana as found in Super 23, the recommended dose is typically two tablets per day. Those sensitive to Paullinia cupana may choose to take one tablet daily. It's vital to account for caffeine intake from all sources throughout the day to ensure appropriate supplement dosage.


Methods of Consuming Paullinia cupana

Guarana supplements come in various forms, with the method of consumption largely depending on the product. Consuming Paullinia cupana early in the morning or just before a workout often yields the best results. 

The following forms of Guarana are readily available on the market:



Convenient and easy to take, Guarana extract is compressed into tablets or capsules. This form allows for precise dosing and is ideal for those seeking a quick and straightforward method to supplement their diet.



Guarana powder can be mixed into beverages or other drinks. Some individuals prefer this form due to its flexibility and the ability to customise the dosage as required.


Drinks and Teas:

Guarana is also found as an ingredient in energy drinks and teas, providing a natural alternative to synthetic sources of caffeine.

It's recommended to always check the product label as different products contain varying concentrations of caffeine in their formulation. Overstepping the recommended dose in hopes of expedited results could potentially lead to adverse effects.


Potential Side Effects of Paullinia cupana

While Guarana is a completely organic and generally safe supplement, it may pose certain side effects in some individuals. Super 23, containing a carefully calibrated dose of Guarana, undergoes rigorous processing and fermentation to produce the final product, with stringent quality and safety tests conducted before its release to the market. However, some individuals with a heightened sensitivity may experience the following side effects due to excessive caffeine intake (6):


Sleep Disturbances:

Overconsumption of caffeine can disrupt sleep patterns, leading to difficulties in falling asleep or maintaining uninterrupted sleep.



 A high caffeine intake can result in symptoms such as anxiety, jitteriness, and restlessness, particularly when caffeine levels in the body begin to drop.


Gastrointestinal Issues: 

Excessive caffeine may cause certain individuals to experience nausea, stomach upset, or diarrhoea.


Elevated Heart Rate and Blood Pressure:

Caffeine has the potential to mildly increase heart rate and blood pressure, a concern for individuals with existing cardiovascular conditions.


Dependency and Withdrawal Symptoms: 

Regular and substantial caffeine consumption can lead to addiction, with abrupt cessation potentially resulting in withdrawal symptoms like headaches and irritability.

To mitigate these potential side effects, it is essential to be mindful of daily dosage and avoid combining the supplement with other caffeine sources to prevent an overdose. Pregnant or nursing women and those with underlying medical conditions are advised to consult a healthcare professional before commencing the supplement.


Final Remarks

Paullinia cupana, or Guarana, is a natural supplement offering a myriad of health benefits. It not only enhances mental alertness and physical energy but also presents the advantage of gradual caffeine release, thus maintaining sustained energy levels in the body. Regular consumption of Paullinia cupana aids in boosting energy, mental health, attention, focus, and cognitive abilities. Moreover, those with weight concerns may benefit from the metabolism-enhancing effects of Paullinia cupana.

The Super 23 supplement, formulated with a blend of organic ingredients known for their health benefits, is designed to promote overall wellness in users. As a product approved by the TGA, Super 23 adheres to stringent standards and biosafety laboratory guidelines in its manufacturing process. The supplement's all-natural composition is precisely crafted to meet the body's specific needs, thereby optimising physical and mental performance. When used judiciously, Guarana, a key component of Super 23, becomes a valuable component of a well-rounded and healthy lifestyle, serving as a natural booster for energy and cognitive functioning.



  1. LiverTox: Clinical and Research Information on Drug-Induced Liver Injury (2023) Guarana. Available at: (Accessed: 25 July 2023).

  2. Lima, N. da S., Teixeira, L., Gambero, A., Ribeiro, M.L. (2018) 'Guarana (Paullinia cupana) Stimulates Mitochondrial Biogenesis in Mice Fed High-Fat Diet', Nutrients, 10(2). doi: 10.3390/NU10020165.

  3. Hack, B., Penna, E.M., Talik, T., Chandrashekhar, R., Millard-Stafford, M. (2023) 'Effect of Guarana (Paullinia cupana) on Cognitive Performance: A Systematic Review and Meta-Analysis', Nutrients, 15(2). doi: 10.3390/NU15020434/S1.

  4. Peixoto, H., Roxo, M., Röhrig, T., Richling, E., Wang, X., Wink, M. (2017) 'Anti-Aging and Antioxidant Potential of Paullinia cupana var. sorbilis: Findings in Caenorhabditis elegans Indicate a New Utilization for Roasted Seeds of Guarana', Medicines, 4(3):61. doi: 10.3390/MEDICINES4030061.

  5. Mattei, R., Dias, R.F., Espínola, E.B., Carlini, E.A., Barros, S.B.M. (1998) 'Guarana (Paullinia cupana): Toxic behavioral effects in laboratory animals and antioxidant activity in vitro', Journal of Ethnopharmacology, 60(2): 111-116. doi: 10.1016/S0378-8741(97)00141-4.

  6. Arantes, L.P., Machado, M.L., Zamberlan, D.C., et al. (2018) 'Mechanisms involved in anti-aging effects of guarana (Paullinia cupana) in Caenorhabditis elegans', Brazilian Journal of Medical and Biological Research, 51(9). doi: 10.1590/1414-431X20187552.
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